Pharma behaving well?

From Evidence In Medicine
February 6, 2012 - 10:28pm

We have known for many years now that patients having an acute coronary syndrome (ACS) do better if they are immediately treated with aspirin, and that they do even better if in addition to that single antiplatelet agent they are also treated with clopidogrel. In 2009, the PLATO trial was published in the NEJM. It was a randomized trial in more than 18,000 people having an ACS, comparing the benefits of adding either clopidogrel or the newer agent ticagrelor to aspirin. Ticagrelor appeared to cause some increased serious bleeding, but overall it reduced a composite endpoint of vascular death, MI,...


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