Vitamin E could fight obesity-related liver disease
From Battle Diabetes
April 26, 2013 - 11:40am
In a sort of "accidental" scientific discovery, researchers found that vitamin E might a potent weapon against obesity-related liver disease.
A group of colleagues at Case Western Reserve University stumbled on the findings while studying how vitamin E deficiency affects the central nervous system. Using liver tissue to test surgical techniques, they were surprised to find that the mice involved in the study were in the critical stages of nonalcoholic stetohepatitis (NASH), which is essentially a condition characterized by inflammation of the liver due to fat accumulation and oxidative stress.
Mice show NASH symptoms
To test the link between vitamin E and liver disease, the team studied a mouse that was genetically engineered to lack a certain protein that regulates vitamin E levels in the body. This animal showed increased fat deposition and liver injury, but when given vitamin E supplements, the NASH symptoms were reversed or minimized.
These findings may have a significant impact on public health," Danny Manor, an associate professor at the Case Western Reserve University School of Medicine, said in a press release, "as the vast majority of adults in the United States do not consume the amount of vitamin E recommended by the National Institute of Medicine."
How it works
It appears that vitamin E works to offer protection through antioxidative properties, which are known to help prevent other types of chronic conditions, such as cancer, Alzheimer's and heart disease. Ther...Continue reading this article »